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Home / Primary Antibodies / IHC Antibodies

Anti-HRH3 Antibody BHA11301498

SKU : BHA11301498

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Mfr.No.	BS2627
Alternative Names	HH3R ; G-protein coupled receptor 97 ; HRH3 ; GPCR97 ; HH3R
Antigen	HRH3
Categories	Primary Antibodies
Chromosome Location	20q13.33
Clonality	polyclonal
Description	Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. The effects of histamine are mediated by a family of G protein-coupled receptors,the Histamine H1, H2, H3 and H4 Receptors. The gene encoding the human Histamine H3 Receptor is located on chromosome 20 and is expressed as six alternative splice variants in thalamus. These isoforms contain either a deletion in the second transmembrane domain or a variable deletion in the third intracellular loop. The existence of multiple H3 Receptor isoforms suggests that H3-mediated effects may be regulated through alternative splicing mechanisms.The H3 Receptor acts as an autoreceptor in the central nervous system (CNS) and modulates histamine synthesis and release.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 300-350 of Human Histamine H3 Receptor.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q9Y5N1
Uniprot	Q9Y5N1
Weight	48 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: Histamine H3 Receptor (P326) polyclonal antibody detects endogenous levels of Histamine H3 Receptor protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC, IF

Description

IHC ; IF

Dilution

IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301498	BS2627	50µl	$190.44		Add to Cart
BHA11301498	BS2627	100µl	$294.44		Add to Cart

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