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Home / Antibodies

Anti-HMGN1 Antibody BHA11303210

SKU : BHA11303210

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Mfr.No.	BS60043
Alternative Names	Non-histone chromosomal protein HMG-14 ; High mobility group nucleosome-binding ; domain-containing protein 1 ; HMGN1 ; HMG14
Categories	Primary Antibodies
Chromosome Location	21q22.2
Clonality	polyclonal
Description	The high-mobility group (HMG) proteins 14 and 17 are abundant chromosomal proteins that bind to nucleosomes and enhance transcription. HMG-14 and HMG-17 also function as architectural elements, which alter the structure of the chromatin fiber and enhance transcription from chromatin templates. HMG-14/17 proteins modify the nucleosomal organization of the 30 nm chromatin fiber and mediate the unfolding of the higher order chromatin structure thereby facilitating access to the underlying DNA sequence. Clustering of architectural elements, such as HMG proteins and linker histone subtypes into distinct domains, may lead to structural and functional heterogeneity along the chromatin fiber. In addition, HMG-14 and HMG-17 have been identified as constitutive components of mouse oocyte and embryonic chromatin that establish a link between the structure of embryonic chromatin and the normal progression of embryonic development .
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human HMGN1.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P05114
Uniprot	P05114
Weight	11 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: HMGN1 polyclonal antibody detects endogenous levels of HMGN1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303210	BS60043	50µl	$190.44		Add to Cart
BHA11303210	BS60043	100µl	$294.44		Add to Cart

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