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Home / Primary Antibodies / IHC Antibodies

Anti-HCAR2/HCAR3 Antibody BHA11301487

SKU : BHA11301487

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Mfr.No.	BS2605
Alternative Names	Hydroxycarboxylic acid receptor 3 ; G-protein coupled receptor 109B ; G-protein coupled receptor HM74 ; G-protein coupled receptor HM74B ; Niacin receptor 2 ; Nicotinic acid receptor 2 ; HCAR3 ; GPR109B ; HCA3 ; HM74B ; NIACR2 ; Hydroxycarboxylic acid receptor 2 ; G-protein coupled receptor 109A ; G-protein coupled receptor HM74A ; Niacin receptor 1 ; Nicotinic acid receptor ; HCAR2 ; GPR109A ; HCA2 ; HM74A ; NIACR1
Antigen	HCAR2/HCAR3
Categories	Primary Antibodies
Clonality	polyclonal
Description	HM74, also known as PUMAG or Puma-g, is a member of the G protein coupled receptor (GPCR) superfamily. In humans, HM74 is encoded by two different genes (GPR109A and GPR109B) that produce proteins, namely HM74A and HM74 (or HM74B), which are 96% homologous. In mice and rats, only one gene encodes the HM74 protein (Gpr109a). HM74 is a G(i) protein-coupled receptor that mediates the metabolic effects of nicotinic acid. Localizing to the cell membrane, HM74 is highly expressed in adipocytes, immune cells and spleen. Like all members of the GPCR superfamily, HM74 contains seven transmembrane domains. HM74 lacks the N-linked glycosylation sites near the N-terminus that are present in other GPCR family members.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 300-350 of Human HM74.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P49019/Q8TDS4
Uniprot	P49019/Q8TDS4
Weight	45 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: HM74 (T327) polyclonal antibody detects endogenous levels of HM74B protein. This antibody also recognizes HM74A protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301487	BS2605	50µl	$190.44		Add to Cart
BHA11301487	BS2605	100µl	$294.44		Add to Cart

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