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Home / Antibodies

Anti-GRIN2C Antibody BHA11303313

SKU : BHA11303313

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Mfr.No.	BS60157
Alternative Names	Glutamate receptor ionotropic ; NMDA 2C ; GluN2C ; Glutamate [NMDA] receptor subunit epsilon-3 ; N-methyl D-aspartate receptor subtype 2C ; NMDAR2C ; NR2C ; NMDAR2C ; GRIN2C
Antigen	GRIN2C
Categories	Primary Antibodies
Chromosome Location	17q25.1
Clonality	polyclonal
Description	Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors exhibit slow kinetsis of Ca2+ ions and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: ε 1, 2, 3, 4 and one ζ subunit. The ζ subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human NMDAε3.
Reactivity	Human, Mouse
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q14957
Uniprot	Q14957
Weight	134 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: NMDAε3 polyclonal antibody detects endogenous levels of NMDAε3 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303313	BS60157	50µl	$190.44		Add to Cart
BHA11303313	BS60157	100µl	$294.44		Add to Cart

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