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Home / Primary Antibodies / IHC Antibodies

Anti-GRIN2C Antibody BHA11302007

SKU : BHA11302007

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Mfr.No.	BS3541
Alternative Names	Glutamate receptor ionotropic ; NMDA 2C ; GluN2C ; Glutamate [NMDA] receptor subunit epsilon-3 ; N-methyl D-aspartate receptor subtype 2C ; NMDAR2C ; NR2C ; NMDAR2C ; GRIN2C
Antigen	GRIN2C
Categories	Primary Antibodies
Clonality	polyclonal
Description	Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors exhibit slow kinetsis of Ca2+ ions and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: ε 1, 2, 3, 4 and one ζ subunit. The ζ subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 956-1008 of Human NMDAε3.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q14957
Uniprot	Q14957
Weight	134 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: NMDAε3 (P986) polyclonal antibody detects endogenous levels of NMDAε3 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC

Description

IHC

Dilution

IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302007	BS3541	50µl	$190.44		Add to Cart
BHA11302007	BS3541	100µl	$294.44		Add to Cart

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