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Home / Antibodies

Anti-GRAP2 Antibody BHA11302258

SKU : BHA11302258

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Mfr.No.	BS3870
Alternative Names	GRB2-related adapter protein 2 ; Adapter protein GRID ; GRB-2-like protein ; GRB2L ; GRBLG ; GRBX ; Grf40 adapter protein ; Grf-40 ; Growth factor receptor-binding protein ; Hematopoietic cell-associated adapter protein ; GrpL ; Protein GADS ; SH3-SH2-SH3 adapter Mona ; GRAP2 ; GADS ; GRB2L ; GRID
Categories	Primary Antibodies
Chromosome Location	22q13.1
Clonality	polyclonal
Description	The Src homology 3 (SH3) region is a small protein domain of approximately 60 amino acids present in a large group of proteins. In general, it exists in association with catalytic domains, as in the nonreceptor protein-tyrosine kinases and phospholipase C-γ, within structural proteins, such as spectrin or myosin, and in small adapter proteins, such as Crk and GRB2. SH3 domains are often accompanied by SH2 domains of 100 amino acids that bind to tyrosine-phosphorylated regions of target proteins, frequently linking activated growth factors to putative signal transduction proteins. Deletion or mutation of SH3 domains generally activates the transforming potential of nonreceptor tyrosine kinases, suggesting that SH3 mediates negative regulation of an intrinsic transforming activity. Gads is an adapter proteins that contains both SH2 and SH3 domains. Gads binds to tyrosine-phosphorylated proteins, such as Shc, and functions to couple these proteins to downstream effectors.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 131-180 of Human Gads.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O75791
Uniprot	O75791
Weight	38 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Gads (N158) polyclonal antibody detects endogenous levels of Gads protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302258	BS3870	50µl	$190.44		Add to Cart
BHA11302258	BS3870	100µl	$294.44		Add to Cart

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