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Home / Antibodies

Anti-GH1 Antibody BHA11303684

SKU : BHA11303684

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Mfr.No.	BS60553
Alternative Names	Somatotropin ; Growth hormone ; GH ; GH-N ; Growth hormone 1 ; Pituitary growth hormone ; GH1
Categories	Primary Antibodies
Chromosome Location	17q23.3
Clonality	polyclonal
Description	Pituitary growth hormone (GH), also designated somatotropin, plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is secreted in a pulsatile pattern which is tightly controlled by the interplay of GH-releasing hormone (GHRH) and somatostatin (SRIF). GHRH and SRIF are the primary hypothalamic factors that determine GH secretion from the somatotroph and regulate GH synthesis and secretory reserve. GH output is also highly sensitive to feedback control by GH itself, as well as by insulin-like growth factor I. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Human growth hormone contains 191 amino acid residues with two disulfide bridges.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human GH1
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P01241
Uniprot	P01241
Weight	25 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: GH1 polyclonal antibody detects endogenous levels of GH1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303684	BS60553	50µl	$190.44		Add to Cart
BHA11303684	BS60553	100µl	$294.44		Add to Cart

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