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Home / Primary Antibodies / Monoclonal Antibodies

Anti-FCGR3A antibody(DMC219), IgG1 Chimeric mAb

SKU : BHA18100109

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DIMA Biotechnology

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Mfr.No.	DMC100219
Background	This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody compleXes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is eXpressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is eXpressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent VIral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. AlternatIVely spliced transcript variants encoding different isoforms have been found for this gene.
Clonality	Monoclonal
Host	Rabbit
Isotype	Human IgG
Reactivity	Human
Solubility	ELISA 1/5000-10000;Flow Cyt 1/100
Synonyms	FCGR3A,CD16A,FCG3,FCGR3,IGFR3
Usage	Research use only

Form	Powder
Purification	Purified from cell culture supernatant by affinity chromatography
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Applications	ELISA,Flow Cyt

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SKU	Supplier No.	Size	Your price	Quantity
BHA18100109	DMC100219	100 ug	$398		Add to Cart
BHA18100109	DMC100219	10 ug	$60		Add to Cart

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