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Home / Antibodies

Anti-FCGR2B Antibody BHA11304529

SKU : BHA11304529

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Mfr.No.	BS61761
Alternative Names	Low affinity immunoglobulin gamma Fc region receptor II-b ; IgG Fc receptor II-b ; CDw32 ; Fc-gamma RII-b ; Fc-gamma-RIIb ; FcRII-b ; CD32 ; FCGR2B ; CD32 ; FCG2 ; IGFR2
Antigen	FCGR2B
Categories	Primary Antibodies
Chromosome Location	1q23.3
Clonality	polyclonal
Description	CD32 (also designated Fc γ RII) is a low affinity receptor for the Fc fragment of aggregated IgG. CD32 is responsible for the clearance of immunocomplexes by macrophages and also plays an important role in the regulation of antibody production by B cells. IgG can noncooperatively bind either one or two highly glycosylated CD32 molecules, and this binding delivers a negative signal for B cells. CD32 exists as several isoforms that are produced by alternative splicing of three distinct genes, A, B, and C. These isoforms are designated Fc γ RIIA, Fc γ RIIB1, Fc γ RIIB3, and Fc γ RIIC. All isoforms are present on monocytes, placental trophoblasts and endothelial cells. In addition, the Fc γ RIIB forms are present on B lymphocytes, and the Fc γ RIIA and Fc γ RIIC forms are found on neutrophils.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 250-300 of Human FCGR2B.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P31994
Uniprot	P31994
Weight	34 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3. Specificity: CD32-B polyclonal antibody detects endogenous levels of CD32-B protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11304529	BS61761	50µl	$190.44		Add to Cart
BHA11304529	BS61761	100µl	$294.44		Add to Cart

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