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Home / Antibodies

Anti-F11 Antibody BHA11303818

SKU : BHA11303818

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Mfr.No.	BS60702
Alternative Names	Coagulation factor XI ; FXI ; Plasma thromboplastin antecedent ; PTA ; F11
Antigen	F11
Categories	Primary Antibodies
Chromosome Location	4q35.2
Clonality	polyclonal
Description	Coagulation Factor XI (FXI) is a glycoprotein produced by platelets and megakaryocytes in the liver and circulates as a zymogen homodimer in plasma. Factor XI is a trypsin-like plasma serine protease that catalyzes the activation of the consolidation phase of blood coagulation through a Thrombin-generated feedback loop. The plasma half-life of Factor XI is about 52 hours, and plasma concentrations are usually 5 mg/l. During hemostasis, the coagulation protease factor (Factor XIa) activates Factor XI. Factor XI deficiency (Hemophilia C) is an injury-related bleeding disorder that leads to a variable bleeding tendency which is inherited in an autosomal recessive manner, though is not completely recessive, because heterozygotes also have a mild but definite bleeding tendency.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human F11
Reactivity	Human, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P03951
Uniprot	P03951
Weight	70 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: F11 polyclonal antibody detects endogenous levels of F11 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303818	BS60702	50µl	$190.44		Add to Cart
BHA11303818	BS60702	100µl	$294.44		Add to Cart

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