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Home / Antibodies

Anti-CXCR1 Antibody BHA11303488

SKU : BHA11303488

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Mfr.No.	BS60349
Alternative Names	C-X-C chemokine receptor type 1 ; CXC-R1 ; CXCR-1 ; CDw128a ; High affinity interleukin-8 receptor A ; IL-8R A ; IL-8 receptor type 1 ; CD_antigen=CD181 ; CXCR1 ; CMKAR1 ; IL8RA
Antigen	CXCR1
Categories	Primary Antibodies
Chromosome Location	2q35
Clonality	polyclonal
Description	IL-8 has been shown to function as a potent neutrophil chemostatic and activating peptide and is an important mediator of inflammatory diseases. Two distinct human IL-8 receptors, designated IL-8RA and IL-8RB have been characterized. Both are expressed at a high level on neutrophils and to a lesser extent on monocytes and myeloid cell lines. In addition, the IL-8RA subunit is expressed in T cells such as the Jurkat cell line. Both IL-8Rs are members of the seven-transmembrane domain rhodopsin superfamily of receptors and as such, couple G proteins for signal transduction. The two receptors share 77% amino acid identity. IL-8RA exhibits high-affinity binding for IL-8 and low-affinity MGSA binding, whereas IL-8RB has high-affinity binding for both IL-8 and MGSA.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human CXCR1
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P25024
Uniprot	P25024
Weight	43 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: CXCR1 polyclonal antibody detects endogenous levels of CXCR1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303488	BS60349	50µl	$190.44		Add to Cart
BHA11303488	BS60349	100µl	$294.44		Add to Cart

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