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Home / Antibodies

Anti-CSF3 Antibody BHA11303671

SKU : BHA11303671

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Mfr.No.	BS60536
Alternative Names	Granulocyte colony-stimulating factor ; G-CSF ; Pluripoietin ; INN: Filgrastim ; INN: Lenograstim ; CSF3 ; C17orf33 ; GCSF
Categories	Primary Antibodies
Chromosome Location	17q21.1
Clonality	polyclonal
Description	Granulocyte-colony stimulating factor, G-CSF, is a pleiotropic cytokine that influences differentiation, proliferation and activation of the neutrophilic granulocyte lineage. The murine G-CSF cDNA encodes a 208 amino acid precursor containing a 30 amino acid signal peptide that is proteolytically cleaved to form a 178 amino acid residue mature protein. Two G-CSF cDNAs, which are identical except for a three amino acid deletion in the N-terminus of one form of the protein, have been isolated from human cells. Murine and human G-CSF share 73% sequence identity at the amino acid level. G-CSF signals through the G-CSF receptor, G-CSFR, a heavily glycosylated 812 amino acid polypeptide with a single transmembrane domain. Stimulation of the G-CSFR results in the activation of the Ras/MAPK pathway and phosphorylation of the adaptor protein Shc. Studies indicate that the kinases Lyn and Syk and the transcription factor Stat3 are activated in response to G-CSF stimulation.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human CSF3.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P09919
Uniprot	P09919
Weight	22 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: CSF3 polyclonal antibody detects endogenous levels of CSF3 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303671	BS60536	50µl	$190.44		Add to Cart
BHA11303671	BS60536	100µl	$294.44		Add to Cart

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