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Home / Primary Antibodies / IHC Antibodies

Anti-CDKN2C Antibody BHA11300436

SKU : BHA11300436

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Mfr.No.	BS1268
Alternative Names	Cyclin-dependent kinase 4 inhibitor C ; Cyclin-dependent kinase 6 inhibitor ; p18-INK4c ; p18-INK6 ; CDKN2C ; CDKN6 ; p18INK4c ; p18INK6 ; p18 INK6
Categories	Primary Antibodies
Chromosome Location	1p32.3
Clonality	polyclonal
Description	The normal progression of cells through the cell cycle is under the control of the cyclin dependent protein kinases Cdk4 and Cdk6 which are subject to inhibition by the mitotic inhibitory protein p16. Isolated members of the p16 family have been designated p15 and p18, respectively. The p16 related protein, p18, interacts strongly with Cdk6 and to a lesser extent with Cdk4, but lacks apparent interaction with other Cdks. Recombinant p18 has been shown to inhibit cyclin D-Cdk6 kinase activity. In contrast to p21/p27 that form ternary complexes with cyclin-Cdks, only binary complexes of p15, p16 and p18 have been identified in association with Cdk4 and/or Cdk6.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 100-150 of Human p18 INK4c.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P42773
Uniprot	P42773
Weight	18 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: p18 INK4c (D142) polyclonal antibody detects endogenous levels of p18 INK4c protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300436	BS1268	50µl	$190.44		Add to Cart
BHA11300436	BS1268	100µl	$294.44		Add to Cart

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