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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD47 Antagonist Antibody

SKU : BHA18200116

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BPS Bioscience

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Mfr.No.	79065-1
Background	Cluster of Differentiation 47, or CD47, plays an essential role in cell growth, death, migration, and adhesion. CD47 binding to SIRP-alpha mediates phagocytosis by sending a "do not eat me" signal to phagocytes. CD47 proteins are often over expressed by tumor cells as a means for them to escape phagocytosis. As a result, cancerous tumor cells have the ability to proliferate and evade the immune system.
Clonality	Monoclonal
Description	Anti-CD47 recombinant human antagonist antibody recognizing the SIRP-alpha or SIRP-gamma binding region of human CD47. This antibody has not been tested for cross-reactivity with any other species.
Formulation	8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Isotype	IgG1
Molecular Weight	Heavy Chain: 51 kDa, Light Chain: 27 kDa
Species	Human

Uniprot	Q08722

Format	Aqueous buffer solution
Purification	Protein A affinity chromato-graphy from HEK293 supernatants.
Shipping Temperature	-80°C (dry ice)
Storage Stability	Stable for at least 12 months at -80°C. Protect from light. Avoid freeze/thaw cycles. Store diluted antibody with carrier protein (BSA 0.1 - 0.5%) at 4°C, stable for 2 weeks.

Product Manual	Datasheet

Reference	1. Vernon-Wilson, E.F. et al., Eur. J. Immunol. 2000; 30(8): 2130-2137. 2. Majeti, R. et al., Cell. 2009; 138(2): 286- 299.

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SKU	Supplier No.	Size	Your price	Quantity
BHA18200116	79065-1	50 ug	$379.50		Add to Cart

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