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Home / Antibodies

Anti-CCL11 Antibody BHA11303620

SKU : BHA11303620

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Mfr.No.	BS60485
Alternative Names	Eotaxin ; C-C motif chemokine 11 ; Eosinophil chemotactic protein ; Small-inducible cytokine A11 ; CCL11 ; SCYA11
Antigen	CCL11
Categories	Primary Antibodies
Chromosome Location	17q12
Clonality	polyclonal
Description	Eotaxin (also designated eotaxin-1) is a member of the C-C or ∫ family of chemokines which is characterized by a pair of adjacent cysteine residues. Eotaxin was first purified from the bronchoalveolar lavage fluid of guinea pigs challenged with an aerosol allergen, and serves as a potent chemoattractant for eosinophils. Eosinophilia is a prominent feature of several allergic conditions and is thought to be a central event in maladies such as bronchial asthma, dermatitis, conjunctivitis and possibly inflammatory bowel disease. The cognate eotaxin receptor has been identified. Originally described as mouse orphan receptor (MIP-1a receptor-like 2), CKR-3 has been shown to not only serve as the high affinity receptor for eotaxin, but also for RANTES and MCP-3. CKR-3 is expressed on the cell surface of primary eosinophils and does not bind to other members of the C-C or C-X-C family of chemokines. CKR-3 also serves as a co-receptor for a restricted subset of viruses.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human CCL11.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P51671
Uniprot	P51671
Weight	11 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: CCL11 polyclonal antibody detects endogenous levels of CCL11 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303620	BS60485	50µl	$190.44		Add to Cart
BHA11303620	BS60485	100µl	$294.44		Add to Cart

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