Anti-caspase 1 Antibody

Mfr.No.	Y058229
Antigen	Caspase 1
Categories	Primary Antibodies
Cellular Localization	Cytoplasm
Clonality	polyclonal
Conjugate	Unconjugated
Description	This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms.
Host	Rabbit
Immunogen	Synthetic peptide conjugated to KLH
Isotype	IgG
Quantity	100 µl
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.02% Sodium Azide
Concentration	100µg/100ul
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

IHC, ELISA

Description

For research use only
Peptide ELISA titer: 1:40,000-1:80,000
Immunohistochemistry: 1:50-200
Optimal dilutions/concentrations should be determined by the end use, IHC ; ELISA

Dilution

ELISA	1:40,000-1:80,000
IHC	1:50-200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10900260	Y058229	100 ul	$217.50		Add to Cart

Anti-caspase 1 Antibody

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