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Home / Antibodies

Anti-ANO1 Antibody BHA11304047

SKU : BHA11304047

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Mfr.No.	BS61052
Alternative Names	Anoctamin-1 ; Discovered on gastrointestinal stromal tumors protein 1 ; Oral cancer overexpressed protein 2 ; Transmembrane protein 16A ; Tumor-amplified and overexpressed sequence 2 ; ANO1 ; DOG1 ; ORAOV2 ; TAOS2 ; TMEM16A
Categories	Primary Antibodies
Chromosome Location	11q13.3
Clonality	polyclonal
Description	TMEM16A, also known as DOG1, ORAOV2, TAOS2 or ANO1 (anoctamin 1), is a 986 amino acid multi-pass membrane protein that localizes to both the cell membrane and the cytoplasm and belongs to the anoctamin family. Expressed in a variety of tissues with highest expression in skeletal muscle and liver, TMEM16A functions as a calcium-activated chloride channel that is required for normal tracheal development. Human TMEM16A shares 90% sequence identity with its mouse counterpart, suggesting a conserved role between species. TMEM16A is present in breast, pancreatic, gastric, and uterine cancers, as well as in neck, ovarian and parathyroid tumors, suggesting a role for TMEM16A in carcinogenesis. Three isoforms of TMEM16A exist due to alternative splicing events.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human ANO1.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q5XXA6
Uniprot	Q5XXA6
Weight	74 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3. Specificity: ANO1 polyclonal antibody detects endogenous levels of ANO1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11304047	BS61052	50µl	$190.44		Add to Cart
BHA11304047	BS61052	100µl	$294.44		Add to Cart

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