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Home / Antibodies

Anti-ACLY Antibody BHA11300858

SKU : BHA11300858

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Mfr.No.	BS1715
Alternative Names	ATP-citrate synthase ; ATP-citrate (pro-S-)-lyase ; ACL ; Citrate cleavage enzyme ; ACLY
Categories	Primary Antibodies
Chromosome Location	17q21.2
Clonality	polyclonal
Description	ATP citrate lyase (ACL) is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer of four identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. One of these products, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. NDPK has been found to phosphorylate ACL and insulin to increase phosphorylation of ACL.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 430-480 of Human ATP-Citrate synthase.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P53396
Uniprot	P53396
Weight	120 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: ATP-citrate synthase (P449) polyclonal antibody detects endogenous levels of ATP-citrate synthase protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IF

Description

WB ; IF

Dilution

WB	1:500-1:1000
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300858	BS1715	50µl	$190.44		Add to Cart
BHA11300858	BS1715	100µl	$294.44		Add to Cart

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