This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti- inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors.
Categories
Primary Antibodies
Cellular Localization
Widely
Clonality
polyclonal
Description
ANXA1, also named as ANX1, LPC1 and p35, belongs to the annexin family. It is a member of the annexin family of Ca2+-binding and phospholipidbinding proteins, and it is particularly abundant in various populations of peripheral blood leukocytes. ANXA1 regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity. ANXA1 is a pleiotrophic protein produced by many cell types including peripheral blood leucocytes. The antibody is specific to ANXA1.
Host
Rabbit
Immunogen
annexin A1
Isotype
IgG
Molecular Weight
38 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Subcellular Location
widely
Synonyms
Annexin 1, annexin A1, Annexin I, ANX1, ANXA1, Calpactin 2, Calpactin II, Chromobindin 9, Lipocortin I, LPC1, p35
Uniprot
P04083
Gene Id
301
Research Area
Immunology, Signal Transduction, Metabolism
Weight
40kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)