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Home / Primary Antibodies / Polyclonal Antibodies

ANGPTL4 antibody

SKU : BHA10800394

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Mfr.No.	FNab00399
Alternative Names	Angiopoietinlike4 ; Angiopoietinlikeprotein4 ; Angiopoietinrelatedprotein4 ; ANGPTL2 ; ANGPTL4 ; ARP4 ; FIAF ; HFARP ; NL2 ; PGAR ; pp1158
Background	Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix(ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation(By similarity).
Categories	Primary Antibodies
Cellular Localization	Extracellular matrix, Secreted
Clonality	polyclonal
Description	Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation (By similarity).
Host	Rabbit
Immunogen	angiopoietin-like 4
Isotype	IgG
Molecular Weight	45 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Subcellular Location	Extracellular matrix, Secreted
Synonyms	Angiopoietin like 4, Angiopoietin like protein 4, Angiopoietin related protein 4, ANGPTL2, ANGPTL4, ARP4, FIAF, HFARP, NL2, PGAR, pp1158, PSEC0166, UNQ171/PRO197

Uniprot	Q9BY76
Gene Id	51129
Research Area	Developmental biology, Immunology, Cardiovascular, Signal Transduction
Weight	45kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC, IF, IP, WB

Description

ELISA ; IHC ; IF ; IP ; WB

Dilution

WB	1:200-1:2000
IHC	1:20-1:200
IF	1:20-1:200
IP	1:200-1:2000

Tested Application

WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200; IP: 1:200-1:2000

Manual	FNab00399.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800394	FNab00399	100ug	$260		Add to Cart

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