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Home / Primary Antibodies

AMPK beta 1 Antibody (PRKAB1) (F50060)

SKU : BHA17101611

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Mfr.No.	F50060, F50060-0.08ML, F50060-0.4ML
Clonality	Polyclonal
Description	The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 4-34 from the human protein was used as the immunogen for this AMPK beta 1 antibody.
Isotype	Ig
Predicted Reactivity	Human, Mouse
Reactivity	Human, Mouse
Recombinant	No

Uniprot	Q9Y478

Format	Purified
Purification	Purified
Storage	Aliquot the AMPK beta 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, ELISA
Dilution	Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17101611-1	F50060-0.08ML	0.08ml	$165		Add to Cart
BHA17101611-2	F50060-0.4ML	0.4ml	$379		Add to Cart

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