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Home / Primary Antibodies / Monoclonal Antibodies

alpha-synuclein antibody

SKU : BHA10809883

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Mfr.No.	FNab09891
Background	Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alteatively spliced transcripts encoding different isoforms have been identified for this gene.
Clonality	monoclonal
Host	Mouse
Immunogen	synuclein, alpha (non A4 component of amyloid precursor)
Immunogen Region	synuclein, alpha (non A4 component of amyloid precursor)
Isotype	IgG1
Molecular Weight	18 kDa
Reactivity	Human, Mouse, Rat
Recommended Dilution	WB: 1:500 - 1:2000; IHC: 1:500 - 1:2000
Synonyms	Alpha synuclein, NACP, PARK1, PARK4, SNCA

Uniprot	P37840
Gene Id	6622
Clone No	5C6
Research Area	Neuroscience

Form	liquid
Purification	protein A+G purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500 - 1:2000; IHC: 1:500 - 1:2000

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09891.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809883	FNab09891	100ug	$280		Add to Cart

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