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Home / Primary Antibodies / Polyclonal Antibodies

Adenylosuccinate lyase antibody

SKU : BHA10800159

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Mfr.No.	FNab00161
Alternative Names	Adenylosuccinase ; adenylosuccinatelyase ; ADSL ; AMPS ; ASASE ; ASL
Background	ADSL(adenylosuccinate lyase) is also named as AMPS, ASase, ASL and belongs to the lyase 1 family. It is an enzyme involved in 2 pathways of purine nucleotide metabolism and catalyzes cleavage of succinyl groups to yield fumarate(PMID:18524658). Defects in ADSL are the cause of adenylosuccinase deficiency(ADSL deficiency). In humans, mutations in ADSL lead to an inborn error of metabolism originally characterized by developmental delay, often with autistic features(PMID:20884265)..The ADSL enzymatic activity is reduced in lymphocytes and red blood cells of the patient with severe psychomotor retardation(PMID:9545543). It has 2 isoforms produced by alternative splicing.
Categories	Primary Antibodies
Cellular Localization	Cytosol
Clonality	polyclonal
Description	ADSL(adenylosuccinate lyase) is also named as AMPS, ASase, ASL and belongs to the lyase 1 family. It is an enzyme involved in 2 pathways of purine nucleotide metabolism and catalyzes cleavage of succinyl groups to yield fumarate(PMID:18524658). Defects in ADSL are the cause of adenylosuccinase deficiency (ADSL deficiency). In humans, mutations in ADSL lead to an inborn error of metabolism originally characterized by developmental delay, often with autistic features(PMID:20884265)..The ADSL enzymatic activity is reduced in lymphocytes and red blood cells of the patient with severe psychomotor retardation(PMID:9545543). It has 2 isoforms produced by alternative splicing.
Host	Rabbit
Immunogen	adenylosuccinate lyase
Isotype	IgG
Molecular Weight	55 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	cytosol
Synonyms	Adenylosuccinase, adenylosuccinate lyase, ADSL, AMPS, ASASE, ASL

Uniprot	P30566
Gene Id	158
Research Area	Metabolism
Weight	55kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF, FC

Description

ELISA ; WB ; IHC ; IF ; FC

Dilution

WB	1:500-1:5000
IHC	1:20-1:200
IF	1:10-1:100

Tested Application

WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800159	FNab00161	100ug	$240		Add to Cart

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