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Home / Primary Antibodies / Polyclonal Antibodies

ACTA2/smooth muscle actin antibody

SKU : BHA10800115

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Mfr.No.	FNab00116
Alternative Names	ASMA ; AAT6 ; ACTA2 ; ACTA2SmoothmuscleActin ; Actin ; aorticsmoothmuscle ; Actin ; aorticsmoothmuscleActin ; ACTSA ; ACTVS ; Alphaactin2
Background	The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Categories	Primary Antibodies
Cellular Localization	Cytoplasm, cytoskeleton
Clonality	polyclonal
Description	ACTA2 (also known as α-smooth muscle actin or α-SMA) belongs to the actin family. Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA2 is primarily expressed in vascular smooth muscle and anti-ACTA2 is commonly used to marker smooth muscle cells. This antibody may cross-react with other isoforms of actins.
Host	Rabbit
Immunogen	actin, alpha 2, smooth muscle, aorta
Isotype	IgG
Molecular Weight	42 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cytoplasm, Cytoskeleton
Synonyms	A SMA, AAT6, ACTA2, ACTA2 Smooth muscle Actin, Actin, aortic smooth muscle, Actin, aortic smooth muscle Actin, ACTSA, ACTVS, Alpha actin 2, Alpha SMA, a-SMA, alpha SMA

Uniprot	P62736
Gene Id	59
Research Area	Developmental biology, Cell Division and Proliferation, Cardiovascular, Immunology, Cancer, Neuroscience
Weight	42kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC, IP, WB, IF, FC

Description

ELISA ; IHC ; IP ; WB ; IF ; FC

Dilution

WB	1:500-1:5000
IHC	1:20-1:200
IF	1:20-1:200
IP	1:500-1:5000

Tested Application

WB: 1:500 - 1:1000; IHC: 1:50 - 1:100

Manual	FNab00116.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800115	FNab00116	100ug	$240		Add to Cart

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