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Home / Primary Antibodies / Polyclonal Antibodies

ABHD2 antibody

SKU : BHA10800048

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Mfr.No.	FNab00049
Alternative Names	ABHD2 ; ProteinPHPS12 ; HS12 ; Lungalpha/betahydrolase2 ; LABH2
Background	Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol(AG) from cell membrane(PubMed:26989199). Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol(1AG) and 2-arachidonoylglycerol(2AG) to glycerol and arachidonic acid(AA)(PubMed:26989199). Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation(PubMed:26989199). May also play a role in smooth muscle cells migration(By similarity).
Categories	Primary Antibodies
Cellular Localization	Membrane
Clonality	polyclonal
Description	Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane (PubMed:26989199). Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA) (PubMed:26989199). Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation (PubMed:26989199). May also play a role in smooth muscle cells migration (By similarity).
Host	Rabbit
Immunogen	abhydrolase domain containing 2
Isotype	IgG
Molecular Weight	48 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Membrane
Synonyms	ABHD2, Protein PHPS1 2, HS1 2, Lung alpha/beta hydrolase 2, LABH2

Uniprot	P08910
Gene Id	11057
Research Area	Metabolism
Weight	48kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:500-1:5000
IHC	1:20-1:200

Tested Application

WB: 1:500-1:5000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800048	FNab00049	100ug	$260		Add to Cart

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