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Home / Primary Antibodies / Monoclonal Antibodies

14-3-3 antibody

SKU : BHA10800002

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Mfr.No.	FNab00002
Alternative Names	14-3-3proteintheta
Background	14-3-3 theta(also known as YWHAQ, or 14-3-3 tau) is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3-3 family members interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms(gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo-and hetero-dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. This antibody was raised against full-length 14-3-3 theta.
Categories	Primary Antibodies
Clonality	monoclonal
Description	14-3-3 theta (also known as YWHAQ, or 14-3-3 tau) is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3-3 family members interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. This antibody was raised against full-length 14-3-3 theta.
Host	Mouse
Immunogen	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Isotype	IgG1
Molecular Weight	28 kDa
Reactivity	Human, Rat, Mouse
Regulatory	RUO
Synonyms	14 3 3, 14 3 3 protein T cell, 14 3 3 protein tau, 14 3 3 protein theta, 1C5, HS1, Protein HS1, YWHAQ

Uniprot	P27348
Gene Id	10971
Clone No	8D2
Research Area	Signal Transduction, Neuroscience
Weight	28kDa

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF

Dilution

WB	1:500-1:5000
IHC	1:20-1:200
IF	1:20-1:200

Tested Application

WB: 1:1000-1:10000; IHC: 1:20-1:200; IF: 1:20-1:200

Manual	FNab00002.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800002	FNab00002	100ug	$260		Add to Cart

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