Anti-von Willebrand Factor / Factor VIII Related-Ag Antibody BHA10205800

Mfr.No.	7450-MSM7-P0
Alternative Names	Coagulation Factor VIII ; Factor VIII Related Antigen ; F8VWF ; von Willebrand Antigen 2 ; von Willebrand Disease (vWD)
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	12p13.31
Clonality	Monoclonal
Description	von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
Host	Mouse
Immunogen	Recombinant fragment of human vWF protein (aa1815-1939) (exact sequence is proprietary)
Positive Control	HUVEC cells or Tonsil
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P04275
Uniprot	440848
Gene Id	7450

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	200µg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab with BSA and Azide at 200μg/ml

Applications

ELISA, FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., ELISA ; FACS ; IF ; IHC-F

Dilution

ELISA	Use Ab at 2-4μg/ml for coating
FACS	0.5-1μg/million cells
IF	0.5-1μg/ml
IHC-F	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10205800	7450-MSM7-P0	20µg	$204.67		Add to Cart
BHA10205800	7450-MSM7-P0	100µg	$393.20		Add to Cart

Anti-von Willebrand Factor / Factor VIII Related-Ag Antibody BHA10205800

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