Anti-VEGF (Vascular Endothelial Growth Factor) Antibody BHA10205717

Mfr.No.	7422-MSM1-P1ABX
Alternative Names	MVCD1 ; Vascular Endothelial Growth Factor A (VEGF-A) ; Vascular Permeability Factor (VPF) ; VEGFA
Categories	Primary Antibodies
Cellular Localization	Cell Surface, Cytoplasmic, Extracellular(secreted)
Chromosome Location	6p12
Clonality	monoclonal
Description	This MAb recognizes proteins of 19-22kDa (reducing) and 38kDa-44kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.
Host	Mouse
Immunogen	Human VEGF189 recombinant protein
Positive Control	Tumor cells in astrocytomas, breast or ovarian carcinomas.
Reactivity	Human, Mouse, Rat, Rabbit, Dog
Recombinant	FALSE
Regulatory	RUO

Swissprot	P15692
Uniprot	73793
Gene Id	7422

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., IF ; IHC-F

Dilution

IF	1-2μg/ml
IHC-F	2-4μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10205717	7422-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-VEGF (Vascular Endothelial Growth Factor) Antibody BHA10205717

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