CD79 (also designated Ig ?/Ig ?) is a heterodimer composed of ? chains, designated CD79A or MB-1, and ? chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.
Host
Mouse
Immunogen
Recombinant fragment of human CD79b protein (around aa 29-159) (exact sequence is proprietary)
Isotype
IgG1 Kappa
Positive Control
Daudi or Ramos cells. Germinal center B-cells in a lymph node or tonsil.
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Species
Homo Sapiens (Human)
Swissprot
P40259
Gene Id
974
Clone No
IGB, 1843
Symbol
CD79B
Weight
39kDa
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Applications
ELISA, WB
Description
Order Ab without BSA, Optimal dilution for a specific application should be determined., ELISA ; WB
Dilution
ELISA
Use Ab at 2-4μg/ml for coating
Western Blotting
1-2μg/ml
No Description Available.
No Description Available.
Reviews of Anti-undefined Antibody IGB,1843 Unconjugated BHA10208146