Anti-undefined Antibody 39f Unconjugated BHA10208071

Mfr.No.	546-MSM1-P1ABX
Alternative Names	Alpha thalassemia/mental retardation syndrome X linked homolog ; ATP-dependent helicase ATRX ; ATR2 ; ATRX ; DNA-dependent ATPase and helicase ; MRXHF1 ; RAD54 ; RAD54L ; SFM1 ; SHS ; Transcriptional regulator ATRX ; X-linked helicase II ; X-linked nuclear protein ; XH2 ; XNP ; Znf-HX
Categories	Primary Antibodies
Cellular Localization	Nuclear
Chromosome Location	Xq21.1
Clonality	monoclonal
Description	ATRX is a member of the Snf2 family of helicase/ATPases, which contribute to the remodeling of the nucelosome structure in an ATP-dependent manner, and facilitate the initiation of transcription and replication. Structurally, ATRX contains a PHD zinc finger motif. ATRX is regulated throughout the cell cycle where it is differentially distributed within the nucleus. During interphase, ATRX predominately associates with the nuclear matrix, while during mitosis, ATRX localizes with condensed chromatin. At the onset of M phase, phosphorylation rapidly induces this redistribution of ATRX to the short arms of human acrocentric chromosomes, where it then specifically complexes with heterochromatin protein 1 ? to mediate chromosomal segregation. Mutations in the ATRX gene correlate with a high incidence of severe X-linked form of syndromal mental retardation associated with ? thalassemia or ATRX syndrome
Host	Mouse
Immunogen	Recombinant full-length human ATRX protein
Isotype	IgG1 Kappa
Positive Control	Raji, HeLa or A431 Cells. Pancreas, Adrenal, Ovary, Kidney, Prostate or Stomach.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P46100
Gene Id	546
Clone No	39f
Symbol	ATRX
Weight	280kDa

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Applications

IHC-F

Description

Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., IHC-F

Dilution

Immunohistology (Formalin-fixed)

1-2μg/ml for 30 minutes at RT

No Description Available.

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10208071	546-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-undefined Antibody 39f Unconjugated BHA10208071

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