Anti-TGF-beta (Transforming Growth Factor beta) Antibody BHA10205275

Mfr.No.	7040-MSM2-P1ABX
Alternative Names	ARVD ; BSC 1 cell growth inhibitor ; CED ; Cetermin ; Diaphyseal dysplasia 1 (DPD1) ; Glioblastoma derived T cell suppressor factor (G TSF) ; Latency-associated peptide (LAP) ; Polyergin ; Transforming growth factor beta 1 (TGF beta1 or TGFB1) ; Transforming growth factor beta 2 (TGF beta2 or TGFB2)
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic, Extracellular(secreted)
Chromosome Location	19q13.1 (beta1); 1q41 (beta2); 14q24 (beta3)
Clonality	monoclonal
Description	This MAb recognizes TGF beta 1, 2 and 3. Three TGFĪ �s have been identified in mammals. TGFĪ �1, TGFĪ �2 and TGFĪ �3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFĪ � requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFĪ �3 protein has approximately 80% identity to the mature region of both TGFĪ �1 and TGFĪ �2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGFĪ �ā€™s inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.Ā
Host	Mouse
Immunogen	Bovine TGF-beta2 protein
Isotype	IgG1 Kappa
Positive Control	Salivary gland carcinoma
Reactivity	Human, Monkey, Cow, Dog, Mouse, Rat, Hamster
Recombinant	FALSE
Regulatory	RUO

Swissprot	P01137; P10600; P61812
Uniprot	645227
Gene Id	7040;7042;7043

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

Neut, Functional Assay

Description

Cytokine Neutralization (Order Ab without BSA/Azide); Functional Assay (Order Ab without BSA/Azide); Optimal dilution for a specific application should be determined., Neut ; Functional Assay

Dilution

Neut
Functional Assay

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SKU	Supplier No.	Size	Your price	Quantity
BHA10205275	7040-MSM2-P1ABX	100µg	$393.20		Add to Cart

Anti-TGF-beta (Transforming Growth Factor beta) Antibody BHA10205275

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