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Home / Primary Antibodies / Phospho Antibodies

Anti-Stat3 Antibody (Stat3Y705-B12) Unconjugated BHA10600147

SKU : BHA10600147

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Abwiz Bio Inc.

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Mfr.No.	1121
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	monoclonal
Description	Stat3 is a key signaling molecule for many cytokines and growth-factor receptors and is required for murine fetal development. Stat3 is constitutively activated in several human tumors and may be involved in oncogenic and anti-apoptotic functions. Phospho Stat3 is activated by phosphorylation at Tyr705, which induces dimerization, nuclear translocation and DNA binding. Phospho Stat3 isoform expression appears to reflect biological function: the relative expression levels of Stat3α (86 kDa) and Stat3β (79 kDa) depend on cell type, ligand exposure or maturation stage of the cells. Notably, Stat3β lacks the serine phosphorylation site within the carboxy-terminal transcriptional activation domain.
Host	Rabbit
Immunogen	A synthetic phospho-peptide corresponding to residues surrounding Tyr705 of human phospho Stat3
Isotype	IgG1 Kappa
Modification	phospho-Tyr705
Reactivity	Mouse, Human
Reregulatory	RUO

Clone No	Stat3Y705-B12

Buffer	1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA
Concentration	0.5mg/ml
Dilutions	1.0 - 0.1 µg/ml
Storage	-20ºC

Applications	FACS
Description	FACS

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SKU	Supplier No.	Size	Your price	Quantity
BHA10600147	1121	200µl	$488.10		Add to Cart
BHA10600147	1121	20µl	$220.67		Add to Cart

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