Anti-SOX2 (Transcription Factor) Antibody BHA10205004

Mfr.No.	6657-MSM1-P1ABX
Alternative Names	ANOP3 ; Delta EF2a ; MCOPS3 (Microphthalmia Syndromic type 3) ; SOX-2 ; SRY (sex determining region Y) box 2 ; SRY related HMG box 2 ; Transcription factor SOX-2 ; ysb
Categories	Primary Antibodies
Cellular Localization	Nuclear
Chromosome Location	3q26.33
Clonality	Monoclonal
Description	SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression.
Host	Mouse
Immunogen	Recombinant human SOX2 protein fragment (aa176-305) (exact sequence is proprietary)
Isotype	IgG2b Kappa
Positive Control	MCF-7 cells or Cervical carcinoma
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P48431
Uniprot	518438
Gene Id	6657

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

ELISA, FACS, IF, WB, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., ELISA ; FACS ; IF ; WB ; IHC-F

Dilution

ELISA	Use Ab at 2-4μg/ml for coating
FACS	0.5-1μg/million cells
IF	1-2μg/ml
WB	0.5-1μg/ml
IHC-F	0.5-1μg/ml for 30 min at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10205004	6657-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-SOX2 (Transcription Factor) Antibody BHA10205004

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