Bpb ; NEF ; S100-A1 ; S100 Alpha Chain ; S100 Beta Chain ; S100 Calcium Binding Protein A1 ; S100 Calcium Binding Protein B ; S100 Calcium Binding Protein Beta Neural
Categories
Primary Antibodies
Cellular Localization
Cytoplasmic
Chromosome Location
1q21.3
Clonality
monoclonal
Description
S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the alpha-chain (i.e. in S-100A and S-100B) but not on the beta-chain of S-100 (i.e. in S-100B). This antibody can be used to localize S-100A in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, epithelial and myoepithelial cells of the breast, salivary and sweat glands. Neoplasms derived from these cells also express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein.
Host
Mouse
Immunogen
Purified human S-100 protein conjugated to methylated BSA
Isotype
IgG1 Kappa
Positive Control
A431 or HT-29 Cells. Brain or Melanoma
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
P23297
Uniprot
515715
Gene Id
6271
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
IF, IHC-F
Description
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., IF ; IHC-F