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Home / Primary Antibodies / Phospho Antibodies

Anti-PPP2CA Antibody BHA11302757

SKU : BHA11302757

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Mfr.No.	BS4867
Alternative Names	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform ; PP2A-alpha ; Replication protein C ; RP-C ; PPP2CA ; PP2Aα ; PP2A α
Antigen	PPP2CA
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	5q31.1
Clonality	polyclonal
Description	In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. The PP2A family comprises subfamily members PP2Aα and PP2Aβ. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human PP2A-α around the phosphorylation site of Tyrosine 307.
Modification	phospho-Y307
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P67775
Uniprot	P67775
Weight	38 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-PP2A-α (Y307) polyclonal antibody detects endogenous levels of PP2A-α protein only when phosphorylated at Tyr307.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302757	BS4867	50µl	$199.33		Add to Cart
BHA11302757	BS4867	100µl	$314.89		Add to Cart

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