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Home / Primary Antibodies / Phospho Antibodies

Anti-POLR2A Antibody BHA11302512

SKU : BHA11302512

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Mfr.No.	BS4246
Alternative Names	DNA-directed RNA polymerase II subunit RPB1 ; RNA polymerase II subunit B1 ; DNA-directed RNA polymerase II subunit A ; DNA-directed RNA polymerase III largest subunit ; RNA-directed RNA polymerase II subunit RPB1 ; POLR2A ; POLR2
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	17p13.1
Clonality	polyclonal
Description	RPB1 is a subunit of RNA polymerase II which catalyses transcription of RNA from DNA. RPB1 forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human Rpb1 around the phosphorylation site of Serine 1619.
Modification	phospho-S1619
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P24928
Uniprot	P24928
Weight	217, 240 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-Rpb1 (S1619) polyclonal antibody detects endogenous levels of Rpb1 protein only when phosphorylated at Ser1619.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302512	BS4246	50µl	$199.33		Add to Cart
BHA11302512	BS4246	100µl	$314.89		Add to Cart

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