Anti-PGP9.5 / UchL1 Antibody BHA10205663

Mfr.No.	7345-MSM1-P1ABX
Alternative Names	Gracile Axonal Dystrophy ; Neuron Cytoplasmic Protein 9.5 ; Park5 ; Parkinson Disease 5 ; PGP95 ; Protein Gene Product 9.5 ; Ubiquitin Carboxyl-terminal Esterase L1 ; Ubiquitin Carboxyl-terminal Hydrolase Isozyme L1 ; Ubiquitin Thioesterase L1 ; Ubiquitin Thiolesterase L1
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic, Endoplasmic reticulum membrane
Chromosome Location	4p13
Clonality	monoclonal
Description	This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
Host	Mouse
Immunogen	Native UchL1 (PGP9.5) protein from brain
Positive Control	Cerebellum
Reactivity	Human, Mouse, Rat, Cow, Pig
Recombinant	FALSE
Regulatory	RUO

Swissprot	P09936
Uniprot	518731
Gene Id	7345

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

WB, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., WB ; IHC-F

Dilution

WB	0.5-1μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10205663	7345-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-PGP9.5 / UchL1 Antibody BHA10205663

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