Anti-NSE gamma (Neuron Specific Enolase, gamma) Antibody BHA10200942

Mfr.No.	2026-MSM2-P1ABX
Alternative Names	2-phospho-D-glycerate hydrolyase ; ENO2 ; ENOG ; Enolase 2 gamma neuronal ; Enolase2 ; Gamma-enolase ; Neural enolase ; Neuron specific gamma enolase ; Neuron-specific enolase ; NSE
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	12p13
Clonality	Monoclonal
Description	Recognizes a protein of about 50kDa, which is identified as gamma-enolase. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas. It it be usually employed in combination with other markers such as Synaptophysin, Chromogranin A, and Neurofilament.
Host	Mouse
Immunogen	A synthetic peptide corresponding to aa416-433 of human NSE gamma (exact sequence is proprietary)
Isotype	IgG2b
Positive Control	HepG2, SH-SY-5Y, HeLa or Y79 cells. Pancreas, Cerebellum or Pheochromocytoma.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P09104
Uniprot	511915
Gene Id	2026

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution