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Home / Primary Antibodies / IHC Antibodies

Anti-NRBF2 Antibody BHA11308138

SKU : BHA11308138

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Mfr.No.	BS8236
Alternative Names	Nuclear receptor-binding factor 2 ; NRBF-2 ; Comodulator of PPAR and RXR ; NRBF2 ; COPR
Categories	Primary Antibodies
Chromosome Location	10q21.3
Clonality	polyclonal
Description	Nuclear hormone receptors function as transcriptional activators when their cognate ligands are bound. Binding of the appropriate ligand induces a conformational change in the nuclear receptor, allowing it to interact with transcriptional coactivators. NRBF2 (Nuclear receptor-binding factor 2), also known as COPR (Comodulator of PPAR and RXR), is thought to act as a transcriptional coactivator by altering the activity of target nuclear receptors. Highly expressed in the liver, placenta and keratinocytes, NRBF2 can interact with at least 7 nuclear receptors including PPARα, PPARδ and PPARγ. In the presence of a bound ligand, NRBF2 can interact with nuclear receptors RARα, RARγ. and RXRα. NRBF2, which exists as two isoforms due to alternative splicing, is localized to both the nucleus and the cytoplasm.
Host	Rabbit
Immunogen	Recombinant full length Human NRBF2.
Reactivity	Human, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q96F24
Uniprot	Q96F24
Weight	32 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: NRBF2 polyclonal antibody detects endogenous levels of NRBF2 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:2000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308138	BS8236	50µl	$234.89		Add to Cart
BHA11308138	BS8236	100µl	$368.22		Add to Cart

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