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Home / Primary Antibodies / IHC Antibodies

Anti-NPM1 Antibody BHA11302606

SKU : BHA11302606

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Mfr.No.	BS4655
Alternative Names	Nucleophosmin ; Nucleolar phosphoprotein B23 ; Nucleolar protein NO38 ; Numatrin ; NPM1 ; NPM
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	5q35.1
Clonality	polyclonal
Description	Nucleophosmin (NPM; also known as B23, numatrin or NO38) is an abundant phosphoprotein primarily found in nucleoli. It has been implicated in several distinct cellular functions, including assembly and transport of ribosomes, cytoplasmic/nuclear trafficking, regulation of DNA polymerase α activity, centrosome duplication and molecular chaperoning activities. The NPM gene is also known for its fusion with the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. The NPM portion contributes to transformation by providing a dimerization domain, which results in activation of the fused kinase.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human NPM around the phosphorylation site of Threonine 199.
Modification	phospho-T199
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P06748
Uniprot	P06748
Weight	38 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: p-NPM (T199) polyclonal antibody detects endogenous levels of NPM protein only when phosphorylated at Thr199.
Purity	The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302606	BS4655	50µl	$199.33		Add to Cart
BHA11302606	BS4655	100µl	$314.89		Add to Cart

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