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Home / Antibodies

Anti-MAP3K2 Antibody BHA11303230

SKU : BHA11303230

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Mfr.No.	BS60068
Alternative Names	Mitogen-activated protein kinase kinase kinase 2 ; EC=2.7.11.25 ; MAPK/ERK kinase kinase 2 ; MEK kinase 2 ; MEKK2 ; MAP3K2 ; MAPKKK2, MEKK2
Categories	Primary Antibodies
Chromosome Location	2q14.3
Clonality	polyclonal
Description	Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli including growth factors. The MEK kinases (also designated MAP kinase kinase kinases, MKKKs, MAP3Ks or MEKKs) phosphorylate and thereby activate the MEKs (also called MAP kinase kinases or MKKs), including ERK, JNK and p38. These activated MEKs in turn phosphorylate and activate the MAP kinases. The MEK kinases include Raf-1, Raf-B, Mos, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4, ASK 1 (MEK kinase-5) and MAP3K6 (MEK kinase-6). MEK kinase-1 has been shown to phosphorylate MEK-1 via a Raf-independent pathway. Evidence suggests that MEK-3 is preferentially activated by MEK kinase-3 and that MEK-4 is activated by both MEK kinase-2 and MEK kinase-3. MEK kinase-4 has been shown to specifically activate the JNK pathway. ASK 1 activates both MEK-4 and MEK-3/MEK-6 pathways.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human MAP3K2
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q9Y2U5
Uniprot	Q9Y2U5
Weight	75 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: MAP3K2 polyclonal antibody detects endogenous levels of MAP3K2 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303230	BS60068	50µl	$190.44		Add to Cart
BHA11303230	BS60068	100µl	$294.44		Add to Cart

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