Anti-Laminin, gamma 1 (LAMC1) Antibody BHA10202996

Mfr.No.	3915-RTM1X-P1BX
Alternative Names	LAMB2 ; LAMC1 ; Laminin B2 chain ; Laminin gamma 1 ; Laminin gamma 1 chain
Categories	Primary Antibodies
Cellular Localization	Basement Membrane
Chromosome Location	1q31
Clonality	Monoclonal
Description	Laminins are large hetero-trimeric, non-collagenous glycoproteins composed of α, β, and γ chains. This MAb reacts with laminin B2/1 chain of ~210kDa and does not cross-react with other basement membrane components or fibronectin. Its specificity was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs. Epithelial sheets in vivo are separated from the mesenchymal elements of the stroma by a thin layer of a specialized type of extracellular matrix termed the basement membrane (BM). This structure consists of individual components, some of which are ubiquitous in BMs and some are not. The ubiquitous ones comprise laminin (LN), entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms. This MAb stains uniformly all human and murine basement membranes.
Host	Rat
Immunogen	Murine EHS laminin preparation
Isotype	IgG2a Kappa
Positive Control	Normal colon or carcinomas
Reactivity	Human, Mouse
Recombinant	FALSE
Regulatory	RUO

Swissprot	P11047; Q5VYE7; Q6NVY8
Uniprot	609663
Gene Id	3915

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
IHC-F	0.5-1μg/ml for 30 min at RT

Have you used this product?

Rate it now..!!

SKU	Supplier No.	Size	Your price	Quantity
BHA10202996	3915-RTM1X-P1BX	100µg	$393.20		Add to Cart

Anti-Laminin, gamma 1 (LAMC1) Antibody BHA10202996

Contact us to order

Tel

Email

Contact us to order

Tel

Email

Reviews of Anti-Laminin, gamma 1 (LAMC1) Antibody BHA10202996

Rate it now..!!