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Home / Primary Antibodies / Flow Cytometry (FACS)

Anti-Ku (p70/p80) Antibody BHA10201417

SKU : BHA10201417

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NeoBiotechnologies, Inc.

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Mfr.No.	2547-MSM1-P1ABX
Alternative Names	Ku (p70): 70kDa subunit of Ku antigen ; ATP dependent DNA helicase 2 subunit 1 ; ATP-dependent DNA helicase II 70kDa subunit ; CTC box-binding factor 75kDa subunit ; CTC75 ; CTCBF ; DNA repair protein XRCC6 ; G22P1 ; Ku autoantigen, 70kDa ; Ku70
Categories	Primary Antibodies
Cellular Localization	Nuclear
Chromosome Location	22q13.2 (p70); 2q35 (p80)
Clonality	Monoclonal
Description	Recognizes a dimer of two proteins of 70kDa and ~80kDa, identified as two subunits of Ku. This MAb recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
Host	Mouse
Immunogen	Nuclear extract of human HL-60 cells
Isotype	IgG1 Kappa
Positive Control	Human cancer K562, HL-60, HEp-2 or HeLa cells
Reactivity	Human, Primates
Recombinant	FALSE
Regulatory	RUO

Swissprot	P12956; P13010
Uniprot	292493; 388739
Gene Id	2547;7520

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC(af)

Description

Optimal dilution for a specific application should be determined., FACS ; IF ; IHC(af)

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
IHC(af)	0.25-0.5μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201417	2547-MSM1-P1ABX	100µg	$393.20		Add to Cart

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