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Home / Primary Antibodies / Monoclonal Antibodies

Anti-ITGB3 Antibody BHA11309086

SKU : BHA11309086

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Mfr.No.	MB0145
Alternative Names	Integrin beta-3 ; Platelet membrane glycoprotein IIIa ; Short name=GPIIIa ; CD_antigen=CD61 ; ITGB3 ; GP3A ; CD61 ; GPIIIa
Categories	Primary Antibodies
Chromosome Location	17q21.32
Clonality	monoclonal
Description	Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The 16α and 8β subunits heterodimerize to produce more than 20 different receptors. Most Integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain Integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster Integrins by binding to adjacent Integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of Integrinmediated responses.
Host	Mouse
Immunogen	Synthetic peptide, corresponding to the N-terminus of Human Integrin β3.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P05106
Uniprot	P05106
Weight	Predicted band size :87KDaObserved band size:110KDa

Description	Product: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol Specificity: This antibody detects endogenous levels of Integrin β3 and does not cross-react with related proteins
Purity	The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB

1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11309086	MB0145	50µl	$234.89		Add to Cart
BHA11309086	MB0145	100µl	$368.22		Add to Cart

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