G1m Marker ; G2m Marker ; G3m Marker ; G4m Marker ; HDC ; Heavy Chain Disease Protein ; Human Immunglobulin G ; Ig gamma1/2/3/4 Chain C Region ; IGHG1 ; IGHG2
Categories
Primary Antibodies
Cellular Localization
Cell Surface, Cytoplasmic (Secreted)
Chromosome Location
14q32.33
Clonality
Monoclonal
Description
Recognizes a protein of 75kDa, identified as γ heavy chain of human immunoglobulins. It does not cross-react with α (IgA), μ (IgM), ε (IgE), or δ (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin�s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Host
Mouse
Immunogen
Purified human Ig Gamma Chain
Isotype
IgG2a Kappa
Positive Control
293T, Raji or hPBL cells. Tonsil or Spleen.
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
P01857; P01859; P01860; P01861
Uniprot
510635
Gene Id
3500;3501;3502;3503
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
FACS, IF, IHC-F
Description
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F
Dilution
FACS
0.5-1μg/million cells in 0.1ml
IF
0.5-1μg/ml
IHC-F
0.5-1μg/ml for 30 minutes at RT
Reviews of Anti-IgG (Immunoglobulin Gamma Heavy Chain) Antibody BHA10202126