HLA class II histocompatibility antigen DP alpha 1 chain ; HLA DP1A ; HLA SB alpha chain ; HLADP ; HLADPA1 ; HLASB ; HLASB histocompatibility type ; Human MHC class II HLA SB alpha ; Major histocompatibility complex class II DP alpha 1 ; MHC class II DP3 alpha
Categories
Primary Antibodies
Cellular Localization
Cell Surface
Chromosome Location
6p21.3
Clonality
Monoclonal
Description
Recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked α (33-35kDa) and β (27-30kDa) chains. It reportedly reacts with B- & non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders.
Host
Mouse
Immunogen
Non-T, non-B human acute lymphoblastic leukemia REH6 cell line
Isotype
IgG2b Kappa
Positive Control
Raji cells. Tonsil or lymph node
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
P04440
Uniprot
347270
Gene Id
3115
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
FACS, IF, IHC-F
Description
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F
Dilution
FACS
0.5-1μg/million cells in 0.1ml
IF
0.5-1μg/ml
IHC-F
0.5-1μg/ml for 30 minutes at RT
Reviews of Anti-HLA-DP (MHC II) Antibody BHA10201822