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Home / Primary Antibodies / Polyclonal Antibodies

Anti-GM-CSF/CSF2 Antibody Picoband®

SKU : BHA21006806

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Mfr.No.	PA1456, PA1456-10ug, PA1456-Biotin, PA1456-Cy3, PA1456-Dylight488, PA1456-Dylight550, PA1456-Dylight594, PA1456-FITC, PA1456-HRP, PA1456-APC, PA1456-PE, PA1456-iFluor647, PA1456-carrier-free
Alternative Names	Granulocyte-macrophage colony-stimulating factor
Background	GM-CSF, Granulocyte-macrophage colony-stimulating factor, is a protein secreted by macrophages, T cells, mast cells, endothelial cells, and fibroblasts. By fluorescence in situ hybridization, the GM-CSF gene is mapped to 5q31.1. GM-CSF is a cytokine that functions as a white blood cell growth factor. GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes. GM-CSF is an essential regulator of neutrophil function.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-GM-CSF/CSF2 Antibody catalog # PA1456. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human GM-CSF.
Isotype	Rabbit IgG
Molecular Weight	35 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Granulocyte-macrophage colony-stimulating factor;GM-CSF;Colony-stimulating factor;CSF;Molgramostin;Sargramostim;CSF2;GMCSF;
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P04141
Gene Name	CSF2
Sequence	Belongs to the GM-CSF family.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. Le Beau, M. M., Espinosa, R., III, Neuman, W. L., Stock, W., Roulston, D., Larson, R. A., Keinanen, M., Westbrook, C. A.Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases.Proc. Nat. Acad. Sci. 90: 5484-5488, 1993.<br /><br />2. Park, B. K., Zhang, H., Zeng, Q., Dai, J., Keller, E. T., Giordano, T., Gu, K., Shah, V., Pei, L., Zarbo, R. J., McCauley, L., Shi, S., Chen, S., Wang, C.-Y.NF-kappa-B in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF.Nature Med. 13: 62-69, 2007.<br /><br />3. Uchida, K., Beck, D. C., Yamamoto, T., Berclaz, P.-Y., Abe, S., Staudt, M. K., Carey, B. C., Filippi, M.-D., Wert, S. E., Denson, L. A., Puchalski, J. T., Hauck, D. M., Trapnell, B. C.GM-CSF autoantibodies and neutrophil dysfunction in pulmonary alveolar proteinosis.New Eng. J. Med. 356: 567-579, 2007.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006806-1	PA1456	-	100 ug	$370		Add to Cart
BHA21006806-2	PA1456-10ug	Sample	10 ug	$99		Add to Cart
BHA21006806-3	PA1456-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006806-4	PA1456-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006806-5	PA1456-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006806-6	PA1456-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006806-7	PA1456-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006806-8	PA1456-FITC	FITC	100 ug	$570		Add to Cart
BHA21006806-9	PA1456-HRP	HRP	100 ug	$570		Add to Cart
BHA21006806-10	PA1456-APC	APC	100 ug	$670		Add to Cart
BHA21006806-11	PA1456-PE	PE	100 ug	$670		Add to Cart
BHA21006806-12	PA1456-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006806-13	PA1456-carrier-free	carrier-free	100 ug	$370		Add to Cart

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