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Home / Primary Antibodies / Phospho Antibodies

Anti-GATA1 Antibody BHA11302733

SKU : BHA11302733

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Mfr.No.	BS4840
Alternative Names	Erythroid transcription factor ; Eryf1 ; GATA-binding factor 1 ; GATA-1 ; GF-1 ; NF-E1 DNA-binding protein ; GATA1 ; ERYF1 ; GF1
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	Xp11.23
Clonality	polyclonal
Description	GATA1 (Globin transcription factor 1) is a Cys2/Cys2 zinc finger DNA binding protein that is expressed primarily in erythroid, megakaryocytic, mast cells and eosinophilic cells. It belongs to the GATA family of transcription factors. GATA1 is a transcriptional activator which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence [AT]GATA[AG] within regulatory regions of globin genes and of other genes expressed in erythroid cells. The protein also plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. Acquired somatic mutations in GATA1 occur in virtually all children with Down's Syndrome, congenital transient myeloproliferative syndrome (TMD) and acute megakaryocytic leukemia.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human GATA1 around the phosphorylation site of Serine 142.
Modification	phospho-S142
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P15976
Uniprot	P15976
Weight	43 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-GATA-1 (S142) polyclonal antibody detects endogenous levels of GATA-1 protein when phosphorylated at Ser142.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IP

Description

WB ; IHC ; IP

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IP	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302733	BS4840	50µl	$199.33		Add to Cart
BHA11302733	BS4840	100µl	$314.89		Add to Cart

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