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Home / Primary Antibodies / Monoclonal Antibodies

Anti-FEN1 Antibody BHA11309120

SKU : BHA11309120

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Mfr.No.	MB0179
Alternative Names	Flap endonuclease 1 ; FEN-1 ; DNase IV ; Flap structure-specific endonuclease 1 ; Maturation factor 1 ; MF1 ; hFEN-1 ; FEN1 ; RAD2
Antigen	FEN1
Categories	Primary Antibodies
Chromosome Location	11q12.2
Clonality	monoclonal
Description	DNA replication, recombination and repair, all of which are necessary for genome stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. FEN-1 (for flap endonuclease) is an endonuclease that specifically cleaves the 5' flap structure of DNA in the process of DNA repair. FEN-1 is highly homologous to yeast Rad2. The C-terminal region of FEN-1 may bind to PCNA, thus allowing FEN-1 to function as an exonuclease in DNA replication.
Host	Mouse
Immunogen	Purified recombinant human FEN-1 protein fragments expressed in E.coli.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P39748
Uniprot	P39748
Weight	Predicted band size:42KDa Observed band size:42KDa

Description	Product: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol Specificity: This antibody detects endogenous levels of FEN1 and does not cross-react with related proteins.
Purity	The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, ICC

Description

WB ; ICC

Dilution

WB	1:1000
ICC	1:1000-500

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11309120	MB0179	50µl	$234.89		Add to Cart
BHA11309120	MB0179	100µl	$368.22		Add to Cart

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