Anti-ETS1 / Antibody BHA10201036

Mfr.No.	2113-MSM1-P1ABX
Alternative Names	Avian erythroblastosis virus E26 (v ets) oncogene homolog 1 ; ETS1 ; EWSR2 ; p54 ; v-ets erythroblastosis virus E26 oncogene homolog 1
Categories	Primary Antibodies
Cellular Localization	Nuclear
Chromosome Location	11q23.3
Clonality	Monoclonal
Description	ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator. The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases, cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells, where it is essential for the maintenance of the normal pool of resting T and B cells. ETS1 expression level and distribution are differentially controlled in resting, activated and apoptotic lymphocytes.
Host	Mouse
Immunogen	Recombinant human ETS1 fragment (aa137-230) (exact sequence is proprietary)
Isotype	IgG
Positive Control	HepG2 and HeLa cells. Tonsil, Skin, Pancreas, Kidney and Lymphoma.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P14921
Uniprot	369438
Gene Id	2113

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA at 1.0mg/ml

Applications

FACS, IF, WB, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes) ,Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
WB	1-2μg/ml for 60 minutes at RT
IHC-F	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201036	2113-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-ETS1 / Antibody BHA10201036

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